I updated Windows 10 Pro on my PC with the latest security update (2020-3, or something like that) the other day, and on the restart, it wouldn't boot back into Windows. After about an hour of troubleshooting, I wound up restoring to an earlier time (earlier that day), then using Safe Mode to get back into Windows, restarting back in to Windows normally, and all was okay. Ten minutes later, it was asking me to restart after installing the update again, and I'm sure to can understand my apprehension to it doing that, but I did the restart and all went well.

Anyway. Having told you my woes the latest Windows update caused for my Windows 10 installation, my Captain Sim products (the 737, 757, 777, and L-1011) are working fine in P3Dv4.5 (4.5.13.32097) after that problem.