I just finished a flight from KCLE to KLGA, using the same VORs and intersections which David Paul wanted someone to test.  Used Plan-G3 to create the plan, saved it, then exported it as an fsx .pln file.  Did not encounter any problems or fatal error issues.  Used the Captain Sim 727-100 with Eastern Airlines livery.  Also using Active Sky Next and FSX Fiber Accelerator.  Hope this is helpful.

Jim Kaye