Hi crado.

Have you added the Captain_Sim.b757.sound.gau to the "Trusted" list?

Try making the following changes to the sound.ini file found in [FSX root folder]\Captain_Sim\757 folder.

From this:

[Common]
Refresh.Time=10
Sound.Directory=Captain_Sim\757\sound
SoundOffWhenSimIsSlew=1
SoundOffWhenSimIsPaused=1
SoundOffWhenSimDialogIsOpen=1
SoundOffWhenSimSoundIsOff=1

to this:

[Common]
Refresh.Time=10
Sound.Directory=Captain_Sim\757\sound
SoundOffWhenSimIsSlew=0
SoundOffWhenSimIsPaused=0
SoundOffWhenSimDialogIsOpen=0
SoundOffWhenSimSoundIsOff=0

I do not need those changes in v4.6, but I did need them for versions 4.2 to 4.4.

Hope this helps.