I just downloaded the 727-200 to add to my 727-100 I've been using for months and has worked fine.  I made my first 727-200 flight but could not get the autopilot to engage.  The cursor "hand" indicated all controls could be used, but the aileron and elevator engage paddles would not work, neither as an autopilot inset nor in VC.  Only the altitude hold switch and the up-down-turn knob seemed to operate but I don't know if they actually functioned.  I made the mod Markoz suggested to the aircraft.cfg file turning power on in [electrical] but it didn't help.
Any other suggestions?  the -200s are unusable right now.
One other minor irritation:  in the views of the passenger cabin there is one overhead locker that is open but I can't close it.  In the -100 I could close all of them.