Hi IflyGr8.

I strongly recommend that you do the 757 FMC Tutorial by aussie HERE. When I first got the 757 Captain I tried this tutorial many times to familiarize myself with program a flight in the FMC and seeing/learning how it functions with the autopilot. Once you have mastered that, you can from and to any place you choose (within the 757's range, of course).

Tim Capps has also done a comprehensive tutorial HERE that is a step by step flight which includes setting up from a cold-n-dark cockpit to shut down at the end of the flight. Note: read the entire Topic because we work through a glitch that was found in the FMC with regards to the transition altitudes on the Approach.

Hope this helps.

Mark