cant say for Mark, but as with 727 i use radio navigation. 707 gives one more nav - Doppler. I dont have INS yet.

So, for typical flight. You take assigned SID, set radios and (usualy it is necessary) make some extra calculations how not to miss intersections.
After takeoff you fly by hand using radio navigation. As you exit SID, intercept required radial. Your flightplan should indicate it. Look pic.

Say you fly Portland to Honolulu. You gona fly above the ocean most of the time. You plan to use radio navigation to coastal beacon ONP VOR. and from that point you will use Doppler Nav.

Exit KPDX SID, and intercept radial 209 of ONP VOR. as you established on course, program Doppler, but dont engage it yet.

Set on Doppler control unit
LEG A ONP VOR- HEMLO waypoint: Heading 220 Distance 136.5
Leg B HEMLO waypoint - HOLOT waypoint Heading 221 Distance 95.6

As you flu over the ONP VOR, engage Doppler NAV and set AP mode to NAV.

You will fly entire route be Doppler NAV, until you arrive inrange of CKH VOR. Then intercept radial 219 and prepare for STAR to PHNL.

Thats the basic idea. This example taken from standard FSX flight planner generated plan for KPDX PHNL, using  high altitude airways route.

Thats fun! same for desert flying ;)

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